EpiPens only need to be left in place now for 3 seconds (not 10 seconds)

Normally it is instructed that EpiPen® and EpiPen® Jr adrenaline (epinephrine) autoinjectors are held in place for 10 seconds and that after removal the site of injection is rubbed.

This advice has now changed. The devices have not changed, just the instruction on the label, which will now include:

  • Reduced injection time from 10 to 3 seconds – this is based on research confirming efficacy and delivery of adrenaline through the 3 second delivery.
  • Removal of the massage step after the injection – this has been found to reduce the risk of tissue irritation.

EpiPen®s with a 10 second label can continue to be used and should not be replaced unless they have been used, are just about to expire or have expired.   All EpiPen®s should now be held in place for 3 seconds, regardless of the instructions on the label.  However, if they are held for 10 seconds it will not affect the way that the adrenaline works. New anaphylaxis action plans with the 3 second delivery time will also be phased in.